Blood and Marrow Transplantation Reviews: Volume 10, Issue 1
INTRODUCTION
by John R. Wingard, MD Editor-in-Chief
The major challenges facing the clinician caring for patients
undergoing hematopoietic cell transplantation are the control of
graft-versus-host disease and opportunistic infections. With the
development of effective strategies to control cytomegalovirus
infection, today invasive fungal infections are the leading
opportunistic infectious pathogens after HCT. It is, therefore,
fitting that the featured topic of this issue addresses the formidable
challenges posed by this posttransplantation complication. At the
Tandem Transplant Meetings in March [2000], a satellite symposium was held to
discuss a variety of issues about fungal infections after allogeneic
stem cell transplantation. This symposium was sponsored by Fujisawa
Healthcare through an unrestricted educational grant. The transcript
of this symposium is the featured topic in this issue. In the initial
presentation, I reviewed the risk factors for invasive fungal
infections and the epidemiologic shifts in fungal pathogens that we
have witnessed during the past decade. Dr. Brown then discussed
pharmacologic and immunologic approaches to antifungal prophylaxis.
Dr. Einsele addressed the formidable task of early detection of
invasive fungal infection and discussed new rapid diagnostic
techniques. In conclusion, Dr. Cagnoni presented recent clinical trial
data as to the use of the lipid formulations of amphotericin B and
discussed the exciting promise of new triazoles and a new class of
antifungal agents, the echinocandins, which are currently in clinical
trials. This symposium offers an up-to-date review of the current
status and promising new diagnostic and treatment modalities that will
likely become available to transplant clinicians in the near future.
To download the full issue in PDF format, click the link below.
 BMTR Volume 10, Issue 1
 Copyright 1995-2010 - Carden Jennings Publishing Co., Ltd. All rights reserved. The material available at this site is for educational purposes only and is NOT intended for any diagnostic, clinically related, or other purpose. Carden Jennings Publishing Co., Ltd., assumes no responsibility for any use or misuse of this material and makes no warranty or representation of any kind with respect to the material available at this site.
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